Poly rc binding protein 4

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August undefined, 2024

WebFeb 26, 2024 · Poly(rC) binding protein 2 (PCBP2), a 39 kDa protein, is a member of the α-globin mRNP stability complex [7, 8]. As a generally known RNA-binding protein, PCBP2 possesses three K homology domains, which are the main RNA-recognition regions [9, 10]. WebSingle-stranded nucleic acid binding protein that binds preferentially to oligo dC (PubMed:7607214, PubMed:12414943). Major cellular poly(rC)-binding protein …

Cellular protein modification by poliovirus: the two faces of …

Webinternal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein … WebPoly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a rela-tive molecular weight of 38 kDa, which is characterized by downregulation in many cancer … high street kensington to olympia

Frontiers Poly(rC)-binding proteins as pleiotropic regulators in ...

WebSynonym(s): Anti-Poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations SDS; AV40943: polyclonal: WB: rabbit, human: 1: Expand. … WebFeb 26, 2024 · Small hairpin RNA-mediated depletion of PCBP2 dramatically decreased the viability of gastric cancer cells. Cyclin-dependent kinase 2 (CDK2) was positively regulated by PCBP2 via a direct 3′ UTR binding pathway as determined using a ribonucleoprotein immunoprecipitation assay and a biotin pulldown assay. CDK2 mediated the promoting … WebFind poly a binding protein and related products for scientific research at MilliporeSigma. US EN. Applications Products ... Synonym(s): Anti-LIP4, Anti-LYST-interacting protein, Anti-MCG10, Anti-RNA binding protein MCG10, Anti-poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations SDS; SAB2500758 ... high street kensington tube map

Advances in poly(rC)-binding protein 2: Structure

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WebDec 8, 2024 · Orthologous to human PCBP4 (poly(rC) binding protein 4). [provided by Alliance of Genome Resources, Apr 2024] Other designations. poly(rC)-binding protein 4, alpha-CP4. GeneRIFs: Gene References Into Functions. the p53-PCBP4-ZFP871 axis represents a novel feedback loop in the p53 pathway. ... WebNov 4, 2024 · PCBP2 post-transcriptionally regulates sortilin expression by binding to a C-rich element in its 3' UTR. Embryos lacking the KH domain poly (C) binding protein, Pcbp2, are selectively deficient in the definitive erythroid lineage. Compared to wild-type controls, transcript splicing analysis of the Pcbp2 (-/-) embryonic liver reveals accentuated ... high street king\u0027s lynnWebThe poly(rC)-binding proteins are a subfamily of KH-domain-containing RNA-binding proteins that bind C-rich pyrimidine tracts and play pivotal roles in a broad spectrum of … high street kensington sydney

"WebApr 9, 2008 · A 5′-terminal cloverleaf RNA structure interacts with poly(rC) binding proteins (PCBPs) to protect uncapped PV mRNA from 5′ exonuclease (K. E. Murray, A. W. Roberts, and D. J. Barton, RNA 7:1126-1141, 2001). In this study, we examined de novo polysome formation using HeLa cell-free translation-replication reactions. " - Poly rc binding protein 4

Poly rc binding protein 4

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WebOct 15, 2024 · Poly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a relative molecular weight of 38 kDa, which is characterized by downregulation in many cancer types. Numerous cases have indicated that PCBP1 could be considered as a tumor suppressor to inhibit tumorigenesis, development, and metastasis. WebFind poly a binding protein and related products for scientific research at MilliporeSigma. US EN. Applications Products Services ... Synonym(s): Anti-LIP4, Anti-LYST-interacting protein, Anti-MCG10, Anti-RNA binding protein MCG10, Anti-poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations ...

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WebAug 5, 2016 · 4. Discussion. Poly(rC) binding protein 2 (PCBP2, also called hnRNP E2 or α-CP2) belongs to the hnRNP-E family of RNA binding proteins that interact with a sequence-specific motif having single-stranded poly(C) tracts. PCBP2 contains a characteristic triple repeat of heterogeneous nuclear ribonucleoprotein K homology (KH)-domain. WebMar 21, 2016 · PCBP4 (Poly(RC) Binding Protein 4) is a Protein Coding gene. Diseases associated with PCBP4 include Maxillary Cancer and Jaw Cancer.Among its related …

WebNov 1, 2024 · Iron chaperones include the multi-functional poly(rC)-binding proteins 1–4 (PCBPs). • PCBP1/2 play roles in iron metabolism, with the roles of PCBP3/4 being less … WebSep 6, 2024 · poly(rC)-binding protein 4, LYST-interacting protein, RNA binding protein MCG10, alpha-CP4. GeneRIFs: Gene References Into Functions. PCBP4 plays important …

WebFeb 28, 2024 · The cellular RNA-binding protein poly(rC)-18 binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5´ 19 untranslated region (UTR), but its importance in the viral life cycle has remained unclear. 20 Herein, we aimed to clarify the role of PCBP1 in the HCV life cycle. WebMay 1, 2024 · Poly rC binding protein 1 (PCBP1) is a multifunctional protein that serves as a cytosolic iron chaperone, binding and transferring iron to recipient proteins in mammalian cells. Although PCBP1 ...

WebPoly(rC)-binding protein 2 (PCBP2) is an RNA-binding protein that is characterized by its ability to interact with poly(C) with high affinity in a sequence-specific manner. PCBP2 …

WebOct 16, 2008 · Europe PMC is an archive of life sciences journal literature. Recombinant hnRNP K-homology (KH) domains 1 and 3 of the poly(rC)-binding protein (PCBP) 2 were purified and assayed for interaction with coxsackievirus B3 RNA in electrophoretic mobility shift assays using in vitro transcribed RNAs which represent signal structures of the 5' … how many days till july 30 2023 high street kitchen lymingtonWebinternal ribosomal entry site (IRES). A cellular protein, the poly(rC) binding protein (PCBP), has been reported to interact with the CL either alone or in combination with viral protein 3CD pro. The formation of the ternary complex is essential for RNA replication and, hence, viral proliferation. PCBP also interacts with stem-loop IV of the IRES, how many days till july 31stWebSep 10, 2009 · Leffers et al. (1995) described the cloning and characterization of 2 cDNAs for poly(rC)-binding proteins, called PCBP1 and PCBP2 (601210) by them. The authors analyzed an EST database for sequences that were predicted to encode a protein with K-homologous (KH) domains. high street laundrette macclesfieldWebPoly(rC)-binding protein 4 is a protein that in humans is encoded by the PCBP4 gene.. This gene encodes a member of the KH domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular … how many days till july 30WebPCBP2 knockdown promotes ferroptosis in malignant mesothelioma. PCBP2 might play important roles in central nervous system pathophysiology after spinal cord injury. that the change of poly (C)-binding proteins protein expression was associated with Schwann cell proliferation after the trauma of the peripheral nervous system. high street kensington holiday innWebApr 12, 2024 · Download Citation Heme oxygenase 1 in erythropoiesis: an important regulator beyond catalyzing heme catabolism Heme oxygenase 1 (HO-1), encoded by the HMOX-1 gene, is the main heme oxygenase ... how many days till july 30th