WebApr 9, 2024 · Data show that retinoblastoma binding protein 8 (CtIP) is a tetrameric protein adopting a dumbbell architecture in which DNA binding domains are connected by long coiled-coils. CtIP is required for faithful replication through telomeres via its roles at stalled replication tracts. WebDec 11, 2013 · During S–G2, breast cancer 1 (BRCA1) and its interacting partner CtBP-interacting protein (CtIP) counteract 53BP1–RIF1 and 53BP1–PTIP complexes to promote DNA end-resection and thus ...
Regulation of ZEB1 Function and Molecular Associations in Tumor …
WebJul 1, 2024 · Human C-terminal-binding protein 1 (CtBP1) was initially identified as a phospho-protein that bound a short Pro-Leu-Asp-Leu-Ser (PLDLS) region in the C … WebSep 8, 2024 · CtBP-interacting protein (CtIP) plays a critical role in controlling the homologous recombination-mediated DNA double-stranded break (DSB) repair pathway through DNA end resection, and recent studies suggest that it also plays a role in mitosis. However, the mechanism by which CtIP contributes to mitosis regulation remains elusive. phlox tall purple
Entry - *604124 - RETINOBLASTOMA-BINDING PROTEIN 8; RBBP8 …
WebZEB1 is also having its own protein-interacting domain that shows its affinity toward Smad, CtBP, and p300-p/CAF. In addition, ZEB1 contains E -boxes, which are responsible to bind cofactors. ZEB1 regulates the targeted gene expression both positively and negatively by recruiting its cofactors [47] . WebJul 18, 2003 · Interactions between CtBP and the polycomb repressors have also been reported, but CtBP was not a component of the polycomb complex isolated by Levine et al. . A recent study showed that the association of CtBP with the polycomb protein PC2 led to its sumoylation ( 16 ), but how this modification alters CtBP function is unknown. WebNov 2, 2024 · Here we describe a hepatic system in this context orchestrated by the transcriptional corepressor C-terminal binding protein 2 (CtBP2) that harbors metabolite … phlox sweet summer purple