WebCryptanshinone inhibits the glycolysis and inhibits cell migration through PKM2/β-catenin axis in breast cancer. / Zhou, Jiefeng; Su, Chih Ming; Chen, Hsin An et al. In: OncoTargets and Therapy, Vol. 13, 2024, p. 8629-8639. Research output: Contribution to journal › … WebJan 1, 1986 · Cryptotanshinone and ferruginol were produced continuously by the immobilized cells. Much of the cryptotanshinone was released into the medium, while most of the ferruginol was retained in the cells. The production of cryptotanshinone and ferruginol by the immobilized cells was about 39% and 61% of those by cell suspensions.
Effective Inhibition of Mitochondrial Metabolism by …
WebAug 25, 2024 · Background Breast cancer is one of the most prevalent gynecologic malignancies worldwide. Despite the high sensitivity in response to chemotherapy, drug resistance occurred frequently in clinical treatment. Cryptotanshinone (CTS) is a herbal medicine and has been identified as an anti-inflammatory and anti-oxidative drug. … WebSep 26, 2013 · Cryptotanshinone inhibited SHP2 with an IC50 of 22.50 μM. Fluorescence titration experiments confirmed that it directly bound to SHP2. Enzymatic kinetic analyses showed that cryptotanshinone was a mixed-type and irreversible inhibitor. This drug was further verified for its ability to block SHP2-mediated cell signaling and cellular functions. greenway cleaning madison wi
In Silico Modeling of the Induction of Apoptosis by …
WebObjective(s): Salvia abrotanoides is considered as a new source of tanshinone-producing plants in Iran. Symbiosis of endophytic fungi with their host plants is an effective tool to promote the growth and secondary metabolism of medicinal herbs. WebJul 21, 2016 · Cryptotanshinone (CPT), a well-known diterpene quinone from the widely used traditional Chinese herb Salvia miltiorrhiza, has been reported therapeutic … WebFeb 24, 2024 · In addition, the structures of compounds arucadiol (2), 15,16-dihydrotanshinone I (4), methyl tanshinonate (5), cryptanshinone (7), 1,2-dihydrotanshinquinone I (9), and tanshinone IIA (10) were characterized by mass spectrometry and X-ray crystallographic analysis, and they were confirmed to be active … greenway cleaning