Btg3 and p27

Author: icih

August undefined, 2024

WebBTG3 was identified as a direct target of miR-142-5p, and re-expression of BTG3 reversed the miR-142-5p-induced cell proliferation. Conclusion: miR-142-5p promoted the proliferation and migration... WebBTG3 overexpression markedly downregulated Cyclin D1 and Cyclin E1 levels, whereas elevated p27. Overexpression of BTG3 arrested the cell cycle at G1 phase, which was abrogated by p27 silencing. Furthermore, migration, invasion and EMT of SW480 cells were significantly suppressed by BTG3 overexpression.

BTG3 suppresses growth of PC3 prostate cancer cells …

WebMar 17, 2024 · microRNA-106b-5p Promotes Cell Growth and Sensitizes Chemosensitivity to Sorafenib by Targeting the BTG3/Bcl-xL/p27 Signaling Pathway in Hepatocellular … WebOct 17, 2013 · BTG3 is a downstream target of p53 and also binds and inhibits E2F1. It connects functionally those two major growth-regulatory pathways. BTG3 triggers acute … interventions of chf

BTG3 suppresses EMT by antagonizing the AKT-GSK3β–β …

WebDownload Table BTG3 expression in colorectal carcinogenesis and subsequent progression from publication: The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of ... Webp27kip1 (p27) is a member of the universal cyclin-dependent kinase inhibitor (CDKI) family. p27 expression is regulated by cell contact inhibition and by specific growth factors, such as transforming growth factor (TGF)-beta. Since the cloning of the p27 gene in 1994, a host of other functions have … newhaistore

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WebAug 9, 2007 · Proper regulation of cell cycle progression is pivotal for maintaining genome stability. In a search for DNA damage-inducible, CHK1-modulated genes, we have identified BTG3 (B-cell t ranslocation g ene … WebBTG3/ANA/APRO4 has been reported to be a tumor suppressor gene in some malignancies. It constitutes important negative regulatory mechanism for Src-mediated … new haisla bridge march 2023WebOct 17, 2013 · To reveal the possible mechanisms for BTG3-regulated cell cycle in HCC, we examined the expressions of CyclinD1 and cyclin-dependent kinase inhibitor p27 in 97H/shBTG3 cells and 7721/BTG3 cells. Western blot showed that BTG3 over-expression resulted in up-regulated p27 and down-regulated CyclinD1, while BTG3 knockdown … new hairy bikers book

"WebSep 16, 2024 · B cell transposition gene 3 (BTG3) is reported to be a tumor suppressor and suppresses proliferation and cell cycle progression. This study aims to analyze the … " - Btg3 and p27

Btg3 and p27

Normalized BTG3 transcription levels. Values are expressed …

WebProteintech p27 P27, supplied by Proteintech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol … WebMay 7, 2024 · Enkhnaran et al. (2024) demonstrated that miR-106b-5p promoted cell proliferation and cell cycle and increased hepatocellular carcinoma cells' resistance to sorafenib through the BTG3/Bcl-xL/p27 ...

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WebAug 14, 2015 · BTG3 overexpression enhances the sensitivity of gastric cancer cells to chemotherapeutic agents. exposed to cisplatin (DDP), MG132, paclitaxel, and SAHA, … WebThe knock sensor is attached to the cylinder block. It senses engine knocking using a piezoelectric element. A knocking vibration from the cylinder block is sensed as …

WebBTG3. BTK. BTN1A1 (ECD) BTN2A1. BTNL2. BTRC / beta TrCP1. BUB1. Babesia / Nuttallia. Bacillus anthracis lethal factor. Bacillus anthracis protective antigen. ... FeLV p27. Feline Coronavirus. Feline Immunodeficiency Virus. Feline Leukaemia Virus p15E. Feline SARS-CoV-2. Ferritin. Ferritin Heavy Chain. Ferritin Light Chain. WebB-cell translocation gene 3 ( BTG3 ) is a member of the antiproliferative BTG gene family and is a downstream target of p53. Here, we show that senescence triggered by BTG3 depletion was...

WebDec 4, 2024 · BTG3 is a direct downstream target of miR-106b-5p. BTG3 overexpression inhibited tumor growth of SW620 cells by suppressing proliferation and inducing apoptosis. It was suggested that down-regulated BTG3 expression might be considered as a marker for colorectal carcinogenesis. WebOct 10, 2002 · Protein Protein BTG3 Gene BTG3 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 252 Protein existence Evidence at protein level Annotation score 4/5 Entry Feature viewer Publications External links History BLAST Align Download Add a publication Entry feedback Function

WebMar 14, 2024 · BTG3 overexpression up- regulated the protein expression of Cyclin E, p16, p27, NF-κB, p38α/β, XIAP, Bcl-2, ATG14 and p53, but down-regulated the mRNA expression of MRP1, BCRP, and mTOR in SW480 and SW620 cells. BTG3 overexpression inhibited tumor growth of SW620 cells by suppressing proliferation and inducing apoptosis.

WebOct 24, 2011 · BTG3 transfectants showed a higher mRNA expression of p27, Bax, 14-3-3, Caspase-3, Caspase-9, Beclin 1, NF-κB, IL-1, -2, -4, -10 and -17, but a lower mRNA expression of p21, MMP-9 and VEGF than ... new haitian movies 2015WebDownload scientific diagram BTG3 suppresses growth of PC3 prostate cancer cells in 3D culture. (a) Characterization of PC3 Tet-On cells that express myc-tagged BTG3 upon the addition of ... new hairy bikers cookbookWebFeb 21, 2015 · BTG3 overexpression up- regulated the protein expression of Cyclin E, p16, p27, NF-κB, p38α/β, XIAP, Bcl-2, ATG14 and p53, but down-regulated the mRNA expression of MRP1, BCRP, and mTOR in ... new haitian movies 2020WebmiR-106b-5p induces sorafenib resistance of HCC cells through BTG3/Bcl-xL/p27. (a) Immunofluorescence staining analysis showed the colocalization of BTG3 and Bcl-xL in MHCC-97L and HCC-LM3 cells. Scale bar represents 15 μm. (b) The co-IP study showing the interaction between BTG3 and Bcl-xL in MHCC-97H cells. IgG was used as a … new hairy crabWebDec 11, 2024 · B-cell-translocation gene 3 ( BTG3) is a member of the BTG gene family, members of which share a conserved N-terminal domain, but have divergent C-terminal domains 13. The conserved N-terminal ... interventions of odWeb(E) Effect of BTG3 kncokdown on cell cycle transition in vitro by flow cytometry. (F) Expression levels of Cyclin D1 and p27 in BTG3-overexpressing and depleting cells by Western blot. new haitian presidential palaceWebSep 16, 2024 · BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and CHK1 (checkpoint kinase 1) activation, whereas BTG3 can be phosphorylated and activated via its interaction with CHK1 as a positive feedback loop ( Cheng et al., 2013 ). interventions of dysphagia